MCB 121 Transcription Factors

Structures initially appear with the proteins in "cartoon" colored as follows : alpha helicies, beta sheets, Zn. DNA is in "wireframe" view. Use the buttons below to manipulate structures (or manipulate the structure directly - see Chime Instructions). Other transcription factors can be viewed by clicking their names below. Most structures show only the DNA-binding domain of the factor.

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DNA as spacefilling model.

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Show DNA and "close" AA residues in spacefill.

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Change Structure to:

Glucocorticoid receptor (Cys Cys Zn finger)

GCN4 (B-Zip (Leu-Zip))

Engrailed (H-T-H, homedomain)

Gal4

Lambda Lambda Repressor (H-T-H)

TFIIIA (Cys His Zn finger)

MAD (B-Zip (Leu-Zip), H-L-H)

MyoD (H-L-H)

Zif (Cys His Zn finger)

NFAT-Fos-Jun complex (B-Zip (Leu-Zip)) plus)

NFKappaB

Serum Response Factor (MADS)

SP1 (Cys His Zn finger, no DNA)

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