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Our Publications
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Kareta, M.S., Botello, Z.M., Ennis, J.J., Chou, C., Chédin, F. (2006) Reconstitution and mechanism of the stimulation of
de novo methylation by human DNMT3L. Journal of Biological Chemistry 281(36):25893-25902 link
Chédin, F., Handa, N., Dillingham, M.S., Kowalczykowski S.C. (2006) The AddAB helicase/nuclease forms a stable complex with its cognate χ sequence during translocation. Journal of Biological Chemistry 281(27):18610-7 link
Chen, ZX., Mann, J.R., Hsieh, CL., Riggs, A.D., Chédin, F. (2005) Physical and functional interactions between the human DNMT3L protein and members of the de novo methyltransferase family. Journal of Cellular Biochemistry 95:902-917 .pdf
Yu K., Chédin F., Hsieh CL., Wilson T., and Lieber M.R. (2003) R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells. Nature Immunology vol. 4 no. 5 pp.442-451 .pdf
Chédin F., Lieber M.R., and Hsieh CL. (2002) The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a. PNAS vol. 99 no. 26 pp.16916–16921 .pdf
Chédin F., and Kowalczykowski S.C. (2002) A novel family of regulated helicases/nucleases from Gram-positive bacteria: insights into the initiation of DNA recombination. Molecular Microbiology. 43:823-834.
Chédin F., Ehrlich S.D., and Kowalczykowski S.C. (2000) The Bacillus subtilis AddAB helicase/nuclease is regulated by its cognate Chi sequence in vitro. Journal of Molecular Biology. 298: 7-20. Chédin F., Seitz E.M., and Kowalczykowski S.C. (1998) A highly conserved DNA-binding motif permits identification of a replication protein A homologue in Archaea. Trends in Biochemical Sciences. 272(23): 273-276. Chédin F., Noirot P., Biaudet V., and Ehrlich S.D. (1998) A 5 base-pair sequence protects DNA from exonucleolytic degradation by AddAB, the RecBCD analogue of Bacillus subtilis. Molecular Microbiology. 29(6): 1369-1377. Pujol C., Chédin F., Ehrlich S.D., and Jannière L. (1998) Inhibition of a naturally occurring rolling-circle replicon in derivatives of the theta replicating plasmid pIP501. Molecular Microbiology. 29(3): 709-718. Tracy R.B., Chédin F., and Kowalczykowski S.C. (1997). The recombination hot spot chi is embedded within islands of preferred DNA pairing sequences in the E. coli genome. Cell. 90: 205-206. Chédin F., Dervyn E., Ehrlich S.D., and Noirot P. (1997). Apparent and real recombination frequencies in multicopy plasmids: the need for a novel approach in frequency determination. Journal of Bacteriology. 179: 754-761. Chédin F., Dervyn E., Dervyn R., Ehrlich S.D., and Noirot P. (1994). Frequency of deletion formation decreases exponentially with distance between short direct repeats. Molecular Microbiology. 12: 561-569.