Overview
Our research focuses on the development of the avian neural crest. We are particularly interested in the mechanisms that segregate the neural crest lineage from the neural epithelium (epithelial to mesenchymal transition or EMT),
the mechanisms that guide specific neural crest lineages along different migratory pathways, and the control of neural crest cell differentiation. The laboratory uses a number of experimental
approaches to address cellular and molecular aspects of neural crest development including: in-vivo time lapse confocal imaging, in ovo electroporation of expression plasmids, gene knockdown using siRNA, antisense oligonucleotides and morpholinos,
chick gene microarrays, quail-chick chimeras, cell culture, and in vitro embryo culture.
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