SELECTED PUBLICATIONS
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Scholey, J.M., B. Neighbors, J.R. McIntosh and E.D. Salmon (1984) Isolation of microtubules and a dynein-like MgATPase from unfertilized sea urchin eggs. Journal of Biological Chemistry 259:6516-6525. PDF |
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Scholey, J.M., M.E. Porter, P.M. Grissom and J.R. McIntosh (1985) Identification of kinesin in sea urchin eggs, and evidence for its localization in the mitotic spindle. Nature 318:483-486. |
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Porter, M.E., J.M. Scholey, D.L. Stemple, G.P.A. Vigers, R.D. Vale, M.P. Sheetz and J.R. McIntosh (1987) Characterization of the microtubule movement produced by sea urchin egg kinesin. Journal of Biological Chemistry 262:2794-2802. PDF |
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Leslie, R.J., R.B. Hird, L. Wilson, J.R. McIntosh and J.M. Scholey (1987) Kinesin is associated with a nonmicrotubule component of sea urchin mitotic spindles. Proceedings of the National Academy of Sciences (USA) 84:2771-2775. PDF |
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Lye, R.J., M.E. Porter, J.M. Scholey and J.R. McIntosh (1987) Identification of a microtubule-based cytoplasmic motor in the nematode C. elegans. Cell 51:309-318. PDF |
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Cohn, S.A., A.L. Ingold and J.M. Scholey (1987) Correlation between the ATPase and microtubule translocating activities of sea urchin egg kinesin. Nature 328:160-163. PDF |
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Saxton, W.M., M.E. Porter, S.A. Cohn, J.M. Scholey, E.C. Raff and J.R. McIntosh (1988) Drosophila kinesin: Characterization of microtubule motility and ATPase. Proceedings of the National Academy of Sciences 85:1109-1113. PDF |
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Ingold, A.L., S.A. Cohn and J.M. Scholey (1988) Inhibition of kinesin-driven microtubule motility by monoclonal antibodies to kinesin heavy chains. Journal of Cell Biology 107:2657-2667. PDF |
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Cohn, S.A., A.L. Ingold and J.M. Scholey (1989) Quantitative analysis of sea urchin egg kinesin-driven microtubule motility. Journal of Biological Chemistry 264:4290-4297. PDF |
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Scholey, J.M., J. Heuser, J.T. Yang and L.S.B. Goldstein (1989) Identification of globular mechanochemical heads of kinesin. Nature 338:355-357. PDF |
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Wright, B.D., J.H. Henson, K.P. Wedaman, P.J. Willy, J.N. Morand and J.M. Scholey (1991) Subcellular localization and sequence of a sea urchin kinesin heavy chain: Evidence for its association with membranes in the mitotic apparatus and interphase cytoplasm. Journal of Cell Biology 113:817-833. PDF |
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Cole, D.G., W.Z. Cande, R.J. Baskin, D.A. Skoufias, C.J. Hogan and J.M. Scholey (1992) Isolation of a sea urchin egg kinesin-related protein using peptide antibodies. Journal of Cell Science 101:291-301. PDF |
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Wedaman, K.P., A.E. Knight, J. Kendrick-Jones and J.M. Scholey (1993) Sequences of sea urchin kinesin light chain isoforms. Journal of Molecular Biology 231:155-158. PDF |
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Hogan, C.J., H. Wein, L. Wordeman, J.M. Scholey, K.E. Sawin and W.Z. Cande (1993) Inhibition of anaphase spindle elongation "in vitro" by a peptide antibody that recognizes kinesin motor domain. Proceedings of the National Academy of Sciences (USA) 90:6611-6615. PDF |
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Wright, B.D., M. Terasaki and J.M. Scholey (1993) Roles of kinesin and kinesin- like proteins in sea urchin early embryonic cell divisions: Evaluation using antibody microinjection. Journal of Cell Biology 123:681-689. PDF |
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Cole, D.G., D.S. Chinn, K.P. Wedaman, K. Hall, T. Vuong and J.M. Scholey (1993) Novel heterotrimeric kinesin related protein purified from sea urchin eggs. Nature 366:268-270. PDF |
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Skoufias, D.A., D.G. Cole, K. P. Wedaman and J.M. Scholey (1994) The carboxyl-terminal domain of kinesin heavy chain is important for membrane binding. Journal of Biological Chemistry 269:1477-1485. PDF |
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Cole, D.G., W.M. Saxton, K.B. Sheehan and J.M. Scholey (1994) A slow homotetrameric kinesin-related motor protein purified from Drosophila embryos. Journal of Biological Chemistry 269:22913-22916. PDF |
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Rashid, D.J., K.P. Wedaman and J.M. Scholey (1995) Heterodimerization of the two motor subunits of the heterotrimeric kinesin, KRP 85/95. Journal of Molecular Biology 252:157-162. PDF |
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Henson, J.H., D.G. Cole, M. Terasaki, D.J. Rashid and J.M. Scholey (1995) Immunolocalization of the hetrotrimeric kinesin-like protein, KRP 85/95 to the mitotic apparatus of sea urchin embryos. Developmental Biology 171(1):182-194 PDF |
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Kashina, A.S., R.J. Baskin, D.G. Cole, K.P. Wedaman, W.M. Saxon and J.M. Scholey (1996) A bipolar kinesin. Nature 379:270-272. PDF |
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Scholey, J.M. (1996) Kinesin-II, A Membrane Traffic Motor in Axons, Axonemes and Spindles. J Cell Biol. 133:1-4 PDF |
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Kashina, A.S., J.M. Scholey, J.D. Leszyk and W.M. Saxton (1996b) An essential bipolar mitotic motor. Nature 384:225. PDF |
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Wedaman, K.P., D.W. Meyer, D.J. Rashid, D.G. Cole and J.M. Scholey (1996) Sequence and submolecular localization of the 115-kD accessory subunit of the heterotrimeric kinesin-II (KRP85/95) complex. Journal of Cell Biology 132(3):371-380. PDF |
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Bi, G-Q., R.L. Morris, G. Liao, J.M. Alderton, J.M. Scholey and R.A. Steinhardt (1997) Kinesin- and myosin-driven steps of vesicle recruitment for CA2+-regulated exocytosis. Journal of Cell Biology 138(5):999-1008. PDF |
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Morris, R.L. and J.M. Scholey (1997) Heterotrimeric kinesin-II is required for the assembly of motile 9+2 ciliary axonemes on sea urchin embryos. Journal of Cell Biology 138(5):1009-1022. PDF |
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Sharp, D. J., K.L. McDonald, H.M. Brown, H.J. Matthies, C. Walczak, R.D. Vale, T.J. Mitchison and J.M. Scholey (1999) The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles. Journal of Cell Biology 144:125-138. PDF |
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Signor, D., K.P. Wedaman, L.S. Rose and J.M. Scholey (1999) Two heteromeric kinesin complexes in chemosensory neurons and sensory cilia of Caenorhabditis elegans. Molecular Biology of the Cell 10:345-360. PDF |
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Orozco, J., K.P. Wedaman, D. Signor, H. Brown, L.S. Rose and J.M. Scholey (1999) Movement of motor and cargo along cilia. Nature 398:674. PDF |
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Sharp, D.J., C. Yu, J. Sisson, W. Sullivan and J.M. Scholey (1999) Antagonistic microtubule sliding motors position mitotic centrosomes in Drosophila embryos. Nature Cell Biology 1:50-54. PDF |
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Signor, D., K.P. Wedaman, J.T. Orozco, N.D. Dwyer, C. I. Bargmann, L.S. Rose, and J.M. Scholey (1999). Role of a class DHC1b dynein in retrograde transport of IFT motors and IFT raft particles along cilia, but not dendrites, in chemosensory neurons of living Caenorhabditis elegans. Journal of Cell Biology. 147:519-530. PDF |
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Signor, D. and J.M. Scholey (2000) Microtubule-based transport in axons, dendrites and axonemes. Essays in Biochemistry. 35:89-102. |
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Sharp, D.J., H. Brown, M. Kwon, G.C. Rogers, G. Holland and J.M. Scholey (2000) Functional coordination of three mitotic motors in Drosophila embryos. Molecular Biology of the Cell. 11:241-253. PDF |
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Sharp, D.J., G.C. Rogers and J.M. Scholey (2000) Cytoplasmic dynein is required for poleward chromosome movement during mitosis in Drosophila embryos. Nature Cell Biology. 2: 922-930. PDF |
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Sharp, D.J., G.C. Rogers and J.M. Scholey. (2000) Microtubule-motors in mitosis. Nature. 407: 41-47. (Commissioned review article) PDF |
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Signor, D., Rose, L.S., and J.M. Scholey (2000) Analysis of the roles of kinesin and dynein motors in microtubule-based transport in the C.elegans nervous system. Methods 22:317-325. PDF |
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Zhou, H.M., Brust-Mascher, I., and J.M. Scholey (2001) Direct visualization of the movement of the monomeric axonal transport motor, UNC-104, along neuronal processes in living C. elegans. Journal of Neuroscience 21:3749-3755. PDF |
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Scholey, J.M., Rogers, G.C., and Sharp, D.J. (2001) Mitosis, microtubules, and the matrix. Journal of Cell Biology 154: 261-266. PDF |
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Brust-Mascher, I., Scholey J.M. (2002) Microtubule flux and sliding in mitotic spindles of Drosophila embryos. Molecular Biology of the Cell. 13:3967-3975. PDF |
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Cytrynbaum, E.N., Scholey, J.M., and A. Mogilner. (2003). A force balance model of early spindle pole separation in Drosophila embryos. Biophysical Journal. 84: 757-769. PDF |
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Scholey, J.M., Brust-Mascher, I., Mogilner A. (2003) Cell division. Nature. 422: 746-52. Review. PDF |
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Scholey, J.M. (2003) Intraflagellar Transport. Ann. Rev. Cell. Dev. Biol. 19: 423-443. PDF |
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Kwon, M.J., S. Morales-Mulia, I. Brust-Mascher, G.C. Rogers, D.J. Sharp, and J.M. Scholey (2004). The chromokinesin, KLP3A, drives spindle pole separation during prometaphase and anaphase, and facilitates chromatid motility. Molecular Biology of the Cell. 15(1):219-33. PDF |
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Rogers GC, Rogers SL, Schwimmer TA, Ems-McClung SC, Walczak CE, Vale RD, Scholey JM, Sharp DJ. (2004) Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase. Nature. 427(6972):364-70. PDF |
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Lawrence, C.J., Dawe, R.K., Christie, K.R., Cleveland, D.W., Dawson, S.C., Endow, S.A., Goldstein, L.S.B., Goodson, H.V., Hirokawa, N., Howard, J., Malmbert, R.L., McIntosh, J.R., Miki, H., Mitchison, T.J., Okada, Y., Reddy, A.S.N. Saxton, W.M., Schliwa, M., Scholey, J.M., Vale, R.D., Walczak, C.E. and Wordeman, L. (2004) A Standardized Kinesin Nomenclature. Journal of Cell Biology. 167: 19-22. PDF |
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Snow, J, Ou, G, Gunnarson, A, Walker, R, Zhou, HM, Brust-Mascher, I and Scholey JM (2004) Two Anterograde Intraflagellar Transport Motors Cooperate to Build Sensory Cilia on C. elegans Neurons. Nature Cell Biol. 6 (11):1109-1113 PDF |
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Brust-Mascher, I., Civelekoglu-Scholey, G., Kwon, M., Mogilner, A., and Scholey, J.M. (2004) Model for Anaphase B: Role of three mitotic motors in a switch from poleward flux to spindle elongation. Proc. Natl. Acad. Sci (USA). 101 (45) 15938-15943. PDF |
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Guangshuo Ou, Oliver E. Blacque, Joshua J. Snow, Michel R. Leroux & Jonathan M. Scholey. (2005) Functional coordination of intraflagellar transport motors. Nature. 2005 Jul 28;436(7050):583-7. PDF |
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Civelekoglu-Scholey, G., Sharp, DJ, Mogilner, A., and Scholey, J.M. (2006) Model of chromosome motility in Drosophila embryos: adaptation of a general mechanism for rapid mitosis. Biophys. J. 90(11):3966-82. PDF |
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Pan, X., Ou G., Civelekoglu-Scholey, G.,Blaque O.E., Endres N.F., Tao, L, Mogilner, A., Leroux, M.R., Vale, R., and Scholey, J.M. (2006) Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors. J. Cell Biol. 174(7):1035-45. PDF |
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Tao L, Mogilner A, Civelekoglu-Scholey G, Wollman R,
Evans J, Stahlberg H, Scholey JM. (2006) A Homotetrameric
Kinesin-5, KLP61F, Bundles Microtubules and Antagonizes Ncd in Motility
Assays. |
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Cheerambathur DK, G Civelekoglu-Scholey, I Brust-Mascher, P Sommi, A Mogilner, and J.M. Scholey. (2007) Quantitative analysis of an anaphase B switch: predicted role for a microtubule catastrophe gradient. J Cell Biol. 177:995-1004 PDF |
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Civelekoglu-Scholey G and J.M. Scholey (2007) Mitotic Motors: Kinesin-5 Takes a Brake. Curr. Biol. 17:R544-R547 PDF |
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Brust-Mascher, I and JM Scholey. (2007) Mitotic Spindle Dynamics in Drosophila. Int. Rev. of Cytology, 259: 139-172. |
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Cheerambathur DK, I Brust-Mascher, G Civelekoglu-Scholey, and J.M. Scholey. (2008) Dynamic partitioning of mitotic kinesin-5 cross-linkers between microtubule-bound and freely diffusing states. J Cell Biol. 182:429-426. PDF |
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van den Wildenberg, SMJL, L Tao, LC Kapitein, CF Schmidt, JM Scholey, and EJG Peterman. (2008) The Homotetrameric Kinesin-5 KLP61F Preferentially Crosslinks Microtubules into Antiparallel Orientations. Curr. Biol. 18: 1860–1864. PDF |
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| Brust-Mascher, I, P. Sommi, D.K. Cheerambathur, and J.M. Scholey (2009) Kinesin-5-dependent poleward flux and spindle length control in Drosophila embryo mitosis. Mol. Biol. Cell 20: 1749-1762. PDF |