Research Interests:

We are interested in understanding how the cellular machines that segregate chromosomes during mitosis are assembled, how resolution of sister chromatids during anaphase is coordinated with cell division and how errors in these processes contribute to human diseases such as cancer.

A movie of a budding yeast cell that has fluorescent chromosomes (Hta1-GFP; green) and tubulin (Tub1-CFP; red). As the cell goes through anaphase it is apparent that not all chromosomal elements are resolved together. (Movie by DK Rozelle)

The lab is located at UC Davis in the College of Biological Sciences, Department of Molecular and Cellular Biology and is affiliated with the BMCDB graduate group. © K.B. Kaplan 2012