Coenzyme Q biosynthetic proteins assemble in a substrate-dependent manner into domains at ER-mitochondria contacts. Subramanian K, Jochem A, Le Vasseur M, Lewis S, Paulson BR, Reddy TR, Russell JD, Coon JJ, Pagliarini DJ, Nunnari J (2019)
J Cell Biol. 2019 Apr 1; doi: 10.1083/jcb.201808044
PMID: 30674579

GRAM domain proteins specialize functionally distinct ER-PM contact sites in human cells.
Besprozvannaya M, Dickson E, Li H, Ginburg KS, Bers DM, Auwerx J, Nunnari J (2018)
Elife. 2018 Feb 22; doi: 10.7554/eLife.31019
PMID: 29469807

Discovery and characterization of selective small molecule inhibitors of the mammalian mitochondrial division dynamin, DRP1.
Mallat A, Uchiyama L, Lewis S, Fredenburg R, Terada Y, Ji N, Nunnari J, Tseng C. (2018)
BBRC. 2018 May 15 doi:10.1016/j.bbrc.2018.03.189

GRAM domain proteins specialize functionally distinct ER-PM contact sites in human cells.
Besprozvannaya M, Dickson E, Li H, Ginburg KS, Bers DM, Auwerx J, Nunnari J. (2018)
Elife. 2018 Feb 22 doi:10.7554/eLife.31019.

Molecular basis for sterol transport by StART-like lipid transfer domains.
Horenkamp FA, Valverde DP, Nunnari J, Reinisch KM. (2018)
EMBO J. 2018 Feb 21 doi: 10.15252/embj.201798002.
PMID: 29467216

Defining the physiological role of SRP in protein-targeting efficiency and specificity.
Costa EA, Subramanian K, Nunnari J, Weissman JS. (2018)
Science. 2018 Feb 9 doi: 10.1126/science.aar3607.


Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER.
Friedman JR, Kannan M, Toulmay A, Jan CH, Weissman JS, Prinz WA, Nunnari J.  (2017)
Dev Cell.  2017 Dec 26  doi:10.1016/j.devcel.2017.11.023

Sterol transporters at membrane contact sites regulate TORC1 and TORC2 signaling.
Murley A, Yamada J, Niles BJ, Toulmay A, Prinz WA, Powers T, Nunnari J.  (2017)
J Cell Biol.  2017 Sept 4  doi:10.1083/jcb.201610032

Mitochondrial hepato-encephalopathy due to deficiency of QIL1/MIC13 (C19orf70), a MICOS complex subunit.
Zeharia A, Friedman JR, Tobar A, Saada A, Konen O, Fellig Y, Shaag A, Nunnari J, Elpeleg O. (2016)
Eur J Hum Genet.  2016 Aug 3  doi:10.1038/ejhg.2016.83

ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells.
Samantha C. Lewis, Lauren F. Uchiyama, Jodi Nunnari. (2016)
Science.  2016 July 15; Vol. 353, Issue 6296  doi:10.1126/science.aaf5549
PMID: 27418514

Ltc1 is an ER-localized sterol transporter and a component of ER-mitochondria and ER-vacuole contacts.
Murley A, Sarsam RD, Toulmay A, Yamada J, Prinz WA, Nunnari J. (2015)
J Cell Biol.  2015 May 25;209(4):539-48  doi:10.1083/jcb.201502033
PMID: 25987606

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture.
Friedman JR, Mourier A, Yamada J, McCaffery JM, Nunnari J.  (2015)
Elife.  2015 Apr 28;4  doi:10.7554/eLife.07739
PMID: 25918844

Editorial overview: Cell regulation: Cell biology, fueling a renaissance in metabolism
Nunnari J, Auwerx J. (2015)
Curr Opin Cell Biol.  2015 Apr;33:vi-vii.  doi:10.1016/
PMID: 25795231

Determinants and functions of mitochondrial behavior.
Labbé K, Murley A, Nunnari J. (2014)
Annu Rev Cell Dev Biol.  2014 Aug 15  doi:10.1146/annurev-cellbio-101011-155756
PMID: 25288115

Mitochondrial form and function.
Friedman JR, Nunnari J. (2014)
Nature.  2014 Jan 16  doi:10.1038/nature12985
PMID: 24429632

ER exit sites are physical and functional core autophagosome biogenesis components.
Graef M, Friedman JR, Graham C, Babu M, Nunnari J. (2013)
Mol Biol Cell.  2013 Aug 7   doi: 10.1091/mbc.E13-07-0381
PMID: 23904270

ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast.
Murley A, Lackner LL, Osman C, West M, Voeltz GK, Walter P, Nunnari J (2013)
Elife.  2013 May 14 2:e00422 doi: 10.7554/eLife.00422
PMID: 23682313

Endoplasmic reticulum-associated mitochondria-cortex tether functions in the distribution and inheritance of mitochondria.
Lackner LL, Ping H, Graef M, Murley A, Nunnari J. (2013)
Proc Natl Acad Sci USA Feb 5; 110(6) E458-67 doi: 10.1073/pnas.1215232110
PMID: 23341591

An integrated structural analysis of dynamin assembly.
Ford M, Nunnari J, Jenni S. (2013)
Microsc Microanal. Jul 18; Suppl 2 48-9 doi: 10.1017/S1431927612002097
PMID: 23177442

Cell Biology. Mitochondrial dynamics and apoptosis--the ER connection.
Hoppins S. and Nunnari J. (2012)
Science 337(6098) 1052-4 doi: 10.1126/science.1224709
PMID: 22936767

Mitochondria: in sickness and in health.
Nunnari J. and Suomalainen A. (2012)
Cell 148 1145-59 doi: 10.1016/j.cell.2012.02.035
PMID: 22424226

Inhibition of Drp1 provides neuroprotection in vitro and in vivo.
Grohm J., Kim S.W., Mamrak U., Tobaben S., Cassidy-Stone A., Nunnari J., Plesnila N. and Culmsee C. (2012)
Cell Death Differ. [Epub ahead of print] doi: 10.1038/cdd.2012.18
PMID: 22388349

A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria.
Hoppins S., Collins S.R., Cassidy-Stone A., Hummel E., DeVay R.M., Lackner L.L., Westermann B., Schuldiner M., Weissman J.S. and Nunnari J. (2011)
J. Cell Biol. 195(2) 323-40 doi: 10.1083/jcb.201107053
PMID: 21987634

The crystal structure of dynamin.
Ford M.G.J., Jenni S. and Nunnari J. (2011)
Nature 477 561-6 doi: 10.1038/nature10441
PMID: 21927001

"This is like totally the most awesome publication EVAH!" Quote by Holly Ping.
ER tubules mark sites of mitochondrial division.
Friedman J.R., Lackner L.L., West M., DiBenedetto J.R., Nunnari J. and Voeltz, G. (2011)
Science 334(6054) 358-62 doi: 10.1126/science.1207385
PMID: 21885730

Mitochondria regulate autophagy by conserved signaling pathways.
Graef M. and Nunnari J. (2011)
EMBO J. 30 2101-14 doi: 10.1038/emboj.2011.104
PMID: 21468027

Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission.
Mears J.A., Lackner L.L., Fang S., Ingerman E., Nunnari J. and Hinshaw J.E. (2011)
Nat. Struct. Mol. Biol. 18 20-6 doi: 10.1038/nsmb.1949
PMID: 21170049

The soluble form of Bax regulates fusion via MFN2 homotypic complexes.
Hoppins S., Edlich F., Cleland M., Banerjee S., McCaffery J.M., Youle R. and Nunnari J. (2011)
Mol. Cell 41 150-60 doi: 10.1016/j.molcel.2010.11.030
PMID: 21255726

Small molecule inhibitors of mitochondrial division: tools that translate basic biological research into medicine.
Lackner L.L. and Nunnari J. (2010)
Chem. Biol. 17 578-83 doi: 10.1016/j.chembiol.2010.05.016
PMID: 20609407

Co-assembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion.
DeVay R.M, Dominguez-Ramirez L., Lackner L.L., Hoppins S., Stahlberg H. and Nunnari J. (2009)
J. Cell Biol. 186 793-803 doi: 10.1083/jcb.200906098
PMID: 19752025

Mechanistic analysis of a dynamin effector.
Lacker L., Horner J. and Nunnari J. (2009)
Science 325(5942) 874-7 doi: 10.1126/science.1176921
PMID: 19679814

An ER-mitochondria tethering complex revealed by a synthetic biology screen.
Kornmann B., Currie E., Collins S.R., Schuldiner M., Nunnari J., Weissman J.S. and Walter P. (2009)
Science 325 477-81 doi: 10.1126/science.1175088
PMID: 19556461

Mitochondrial Outer and Inner Membrane Fusion Requires a Modified Carrier Protein.
Hoppins S., Horner J., Song S., McCaffrey J.M. and Nunnari J. (2009)
J. Cell Biol. 184 569-81 doi: 10.1083/jcb.200809099
PMID: 19237599

Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak dependent mitochondrial outer membrane permeabilization.
Cassidy-Stone A., Chipuk J.E., Ingerman E., Song C., Yoo C., Kuwana T., Kurth M.J., Shaw J., Hinshaw J.E., Green D.R. and Nunnari J. (2008)
Dev. Cell 14 193-204 doi: 10.1016/j.devcel.2007.11.019
PMID: 18267088

Shotgun cross-linking analysis for studying quaternary and tertiary protein structures.
Lee Y.J., Lackner L.L., Nunnari J. and Phinney B.S. (2007)
J. Proteome Res. 6 3908-17 doi: 10.1021/pr070234i
PMID: 17854217

The machines that fuse and divide mitochondria.
Hoppins S., Lackner L. and Nunnari J. (2007)
Annu. Rev. Biochem. 76 751-80 doi: 10.1146/annurev.biochem.76.071905.090048
PMID: 17362197

Mitochondrial Inner Membrane Fusion and Cristae Maintenance Requires the Dynamin-Related GTPase Mgm1.
Meeusen S., DeVay R., Block J., Cassidy-Stone A., Wayson S., McCaffery J.M. and Nunnari J. (2006)
Cell 127 383-395 doi: 10.1016/j.cell.2006.09.021
PMID: 17055438

Mdv1 interacts with assembled Dnm1 to promote mitochondrial division.
Naylor K., Ingerman E., Okreglak V, Hinshaw J.E. and Nunnari J. (2006)
J. Biol. Chem. 281 2177-83 doi: 10.1074/jbc.M507943200
PMID: 16272155

A continuous regenerative coupled GTPase assay for dynamin-related proteins.
Ingerman E. and Nunnari J. (2005)
Methods Enzymol. 404 611-9 doi: 10.1016/S0076-6879(05)04053-X
PMID: 16413304

Dnm1 forms spirals that are structurally tailored to fit mitochondria.
Ingerman E., McCaffrey J.M., Hinshaw J.E. and Nunnari J. (2005)
J. Cell Biol. 170 1021-7 doi: 10.1083/jcb.200506078
PMID: 16186251

Mitochondrial fusion intermediates revealed in vitro.
Meeusen S., McCaffrey J.M. and Nunnari J. (2004)
Science 305 1747-52 doi: 10.1126/science.1100612
PMID: 15297626

The division of endosymbiotic organelles.
Osteryoung K. and Nunnari J. (2003)
Science 302 1698-1704 doi: 10.1126/science.1082192
PMID: 14657485

Evidence for a two membrane-spanning autonomous mitochondrial DNA replisome.
Meeusen S. and Nunnari J. (2003)
J. Cell Biol. 63 503-510 doi: 10.1083/jcb.200304040
PMID: 14597773