About Research Publications People Photos Contact

Rose Lab - Publications

Selected Publications

Basham, Stephen E. and Lesilee S. Rose. 1999. Mutations in ooc-5 and ooc-3 disrupt oocyte formation and the reestablishment of asymmetric PAR protein localization in 2-cell C. elegans embryos. Developmental Biology 215: 253-263.

Basham, Stephen E. and Lesilee S. Rose. 2001. The Caenorhabditis elegans polarity gene ooc-5 encodes a Torsin-related protein of the AAA ATPase superfamily. Development 128(22):4645-4656.

Tsou, Meng-Fu, Adam Hayashi, Leah R. DeBella, Garth McGrath, and Lesilee S. Rose. 2002. LET-99 determines spindle position and is asymmetrically enriched in response to PAR polarity cues in C. elegans embryos. Development, 129: 4469-4481.

Tsou , Meng-Fu Bryan, Wei Ku, Adam Hayashi, and Lesilee S. Rose. 2003. PAR-dependent and geometry-dependent mechanisms of spindle positioning. J Cell Bio1: 160(6):845-55.

Tsou, Meng-Fu Bryan, Adam Hayashi, and Lesilee S. Rose. 2003. LET-99 opposes G/GPR signaling to generate asymmetry for spindle positioning in response to PAR and MES-1/SRC-1 signaling. Development 130(23), 5717-30.

Bergmann, Dominique C., Monica Lee, Barbara Robertson, Meng-Fu Bryan Tsou, Lesilee S. Rose and William B. Wood. 2003. Embryonic handedness choice in C. elegans involves a G-alpha protein encoded by the gpa-16 gene. Development 130(23): 5731-40.

Gönczy, Pierre, and Lesilee S. Rose. 2005. Asymmetric cell division and axis formation in the embryo. In WormBook, ed.The C. elegans Research Community, WormBook, doi/10.1895/wormbook.1.7.1, http://www.wormbook.org.

DeBella, Leah R., Adam Hayashi, and Lesilee S. Rose. 2006. LET-711, the C. elegans NOT1 ortholog, is required for spindle positioning and regulation of microtubule length in embryos. Mol. Biol. Cell 17:4911-4924.

Wu, Jui-Ching, and Lesilee S. Rose. 2007. PAR-3 and PAR-1 inhibit LET-99 localization to generate a cortical band important for spindle positioning in C. elegans embryos. Mol Biol Cell. 18:4470-82

Park, Dae Hwi and Lesilee S. Rose. 2008. Dynamic localization of LIN-5 and GPR-1/2 to cortical force generation domains during spindle positioning. Dev Biol 315, 42-54.

Zhu, Li, James O. Wrabl, Adam P. Hayashi, Lesilee S. Rose and Philip J. Thomas. 2008. The Torsin-family AAA Protein OOC-5 Contains a Critical Disulfide Adjacent to Sensor-II That Couples Redox State to Nucleotide Binding. Mol. Biol. Cell 19:3599-3612.

Wei Li, Leah DeBella, Tugba Guven-Ozkan, Rueyling Lin and Lesilee Rose. 2009. An eIF4E-binding protein regulates katanin protein levels in C. elegans embryos. J Cell Bio 187, 33-42.

Krueger, Lori E., Jui-Ching Wu, Meng-Fu Bryan Tsou and Lesilee S. Rose. Lateral inhibition of cortical pulling forces by LET-99 regulates asymmetric spindle positioning in C. elegans embryos. J Cell Bio 189, 481-95

Hwang Sue Y., Rose Lesilee S. 2010. Control of asymmetric cell division in early C. elegans embryogenesis: teaming-up translational repression and protein degradation. BMB Rep. 243, 69-78.

Espiritu Eugenel B., Krueger Lori E., Ye A, and Rose Lesilee S. 2012. CLASPs function redundantly to regulate astral microtubules in the C. elegans embryo. Dev Bio. 368(2), 242-54.

Espiritu Eugenel B., and Rose Lesilee S. 2013. Caenorhabditis elegans Embryo: Establishment of Asymmetry.. eLS.

VanGompel Michael J.W., Nguyen Ken C.Q., Hall David H., DauerWilliam T., and Rose Lesilee S. 2015. A novel function for the Caenorhabditis elegans torsin OOC-5 in nucleoporin localization and nuclear import. MBoC.