Assistant Project Scientist

The Department of Molecular and Cellular Biology at the University of California, Davis invites applications for one Assistant Project Scientist in the Department of Molecular and Cellular Biology.

Position Description

Research - 85% - The position will focus on elucidating mechanisms of mitochondrial biogenesis. More specifically, the candidate will study the organization of the mitochondrial outer membrane, which will elucidate molecular features of ER-mitochondrial contacts sites in human cells. The candidate will design and perform experiments using a suite of advanced proteomics, genetics, high-throughput screening, and quantitative imaging. This position requires a strong background in proteomic methods, CRISPR/Cas9-mediated genome editing, lentivirus-mediated cell transduction, mammalian tissue culture, and mitochondrial cell biology to successfully execute these experiments.

The successful applicant will be responsible for performing publication-quality experiments aimed at studying the cellular and molecular mechanisms underlying the regulated assembly nuclear envelope proteins in cells. Approaches include plasmid cloning, development of CRISPR cell lines, forward CRISPR screens in tissue culture, quantitative microscopy, AI software for image processing, and nuclear polarization assays in tissue cultured fibroblasts.

Professional Competence - 8% - The applicant must have experience with writing manuscripts. They will prepare figures and text for grants and manuscripts. They will also prepare figures for presentations and annual reports to granting agencies. They will also edit and critique papers and grants from others in the lab.

University and Public Service - 7% - Attend 1-2 conferences per year to present our lab's findings to the scientific community. The applicant will train younger postdocs, graduate students, and undergraduates in tissue culture and CRISPR techniques in the lab. The candidate must be able to lead a small team, teach others, and work in small groups

Basic Qualifications

Applicants will have a Ph.D. degree and at least five years of postdoctoral training in molecular biology or a related field with laboratory research experience using CRISPR/Cas9 to edit the genomes of mammalian tissue culture cells. They must also have experience with general cloning and molecular biology skills. The candidate should have a track record demonstrating their interests in the molecular and cell biology of the nucleus. It is essential that all applicants be able to keep a complete and detailed laboratory notebook (digital or analog) of experimental procedures and data to archive, label and document data for publication, proposals and presentations.

Minimum Qualifications

  • Scientific training and skill equivalent to five years post-doctoral experience in molecular biology, and nuclear cell biology.
  • Expertise in mammalian tissue cell culture and CRISPR/Cas9-mediated genome editing.
  • Experience with molecular biology techniques including DNA extraction, DNA sequencing, electrophoresis, lentiviral transduction, PCR, site-directed mutagenesis, and transformations.
  • Experience with record keeping and data storage.
  • Experience with Adobe Illustrator, ImageJ, Microsoft Word, and Microsoft Excel or equivalents.
  • At least 5 years of experience as a postdoctoral researcher in the field of nuclear cell biology

Salary Range

Step I-VI $63,100-$81,200 [100% annual], commensurate with qualifications and experience

Position Available - Closing Date

For full consideration, all application materials must be received by August 2, 2021. The job will remain open until filled.

Term of Appointment

May be made up to 100%

To Apply

Qualified applicants should upload CV, and Cover Letter and contact information of three references via this URL:

https://recruit.ucdavis.edu/apply/JPF04283

Questions

Please direct questions to Dr. Jodi Nunnari, jmnunnari@ucdavis.edu

Disclaimer

The University of California, Davis commits to inclusion excellence by advancing equity, diversity and inclusion in all that we do. We are an Affirmative Action/Equal Opportunity employer, and particularly encourage applications from members of historically underrepresented racial/ethnic groups, women, individuals with disabilities, veterans, LGBTQ community members, and others who demonstrate the ability to help us achieve our vision of a diverse and inclusive community.

Under Federal law, the University ofCalifornia may employ only individuals who are legally able to work in the United States as established by providing documents as specified in the Immigration Reform and Control Act of 1986. Certain UCSC positions funded by federal contracts or sub-contracts require the selected candidate to pass an E-Verify check. More information is available http://www.uscis.gov/e-verify.

UC Davis is a smoke & tobacco-free campus (http://breathefree.ucdavis.edu/). If you need accommodation due to a disability, please contact the recruiting department.