Research in the Department of Molecular and Cellular Biology explores the fundamental mechanisms that drive life at the molecular, cellular, and organismal levels. Faculty investigate a broad range of biological processes—from gene regulation and protein structure to cell signaling, development, and metabolism—using diverse model systems across plants, animals, and microbes. The department emphasizes interdisciplinary approaches and cutting-edge technologies, including advanced light and electron microscopy, to study the dynamic interactions of molecules and cells. This research informs our understanding of health, disease, and evolution, while also contributing to innovative solutions in biotechnology and medicine.
Research
Department Research Cores
Biological Electron Microscopy Facility
This facility supports high-resolution structural biology of single-particle samples by providing access to cryo-electron microscopy sample preparation, imaging capabilities, data collection, and data analysis services. Located in Briggs Hall, the facility offers training and services to on campus and external users. Equipment housed within the facility includes a Glacios TEM and GP2 and Vitrobot plunge freezing devices. Grids can be automatically screened using Smartscope software.
MCB Light Microscopy Core Facility
This facility offers advanced fluorescence microscopy tools, specializing in live-cell imaging and super-resolution techniques. Researchers have access to cutting-edge instruments like lattice light sheet, spinning disk confocal and SIM microscopes, as well as high-throughput imaging platforms, and optical trapping.
