The Department of Molecular and Cellular Biology is home to two advanced research cores that support cutting-edge exploration of cellular structures and dynamics. These facilities provide researchers with powerful tools to visualize life at the molecular level, from high-resolution imaging of macromolecular complexes to live-cell fluorescence microscopy. Access to these state-of-the-art technologies enhances discovery across disciplines and underscores the department’s commitment to advancing foundational and translational bioscience.
Department Research Cores
Department Research Cores
Biological Electron Microscopy Facility
This facility supports high-resolution structural biology of single-particle samples by providing access to cryo-electron microscopy sample preparation, imaging capabilities, data collection, and data analysis services. Located in Briggs Hall, the facility offers training and services to on campus and external users. Equipment housed within the facility includes a Glacios TEM and GP2 and Vitrobot plunge freezing devices. Grids can be automatically screened using Smartscope software.
MCB Light Microscopy Core Facility
This facility offers advanced fluorescence microscopy tools, specializing in live-cell imaging and super-resolution techniques. Researchers have access to cutting-edge instruments like lattice light sheet, spinning disk confocal and SIM microscopes, as well as high-throughput imaging platforms, and optical trapping.